Prof. Dr. Pascal Johann
Prof. Dr. Pascal Johann
Professor für Experimentelle P?diatrie
Kinder- und Jugendmedizin
- Telefon: +49 (0) 821 400-9201
Publikationen
2025
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2024
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2023
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2022
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2021
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2020
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2019
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2018
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2017
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2016
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2015
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2014
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2013
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2012
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2010
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2025 |
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Manea Selma, Fincke Victoria E., Frühwald Michael C., Sturm Dominik, von Zezschwitz Barbara, Johann Pascal-David, Mucha Marlena.
DICER1 mutational spectrum in intracranial CNS-neoplasias - a review and a report from the CNS-InterREST GPOH study center.
https://doi.org/10.3390/cancers17091513
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2024 |
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Fincke Victoria, Lossner Maurice, Sax Irmengard, Mucha Marlena, Dorn Felix, Wudy Stefan, Vokuhl Christian, Claus Rainer, Kunstreich Marina, Slavetinsky Christoph, Fuchs Jorg, Schlesner Matthias, Frühwald Michael, Redlich Antje, Kuhlen Michaela, Johann Pascal.
Analysis of DNA methylation profiles and single nuclei RNA-seq of pediatric adrenocortical tumors reveal subgroups of clinical relevance and distinct tumor biology [Abstract].
https://doi.org/10.1530/endoabs.99.ep27
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Fincke Victoria E., Steinbügl Mona, Chun Hye-Jung E., Nemes Karolina, Mucha Marlena, Lo?ner Maurice, Dorn Felix, Gastberger Katharina, Bühner Sebastian, Sill Martin, Kr?ncke Thomas, Siebert Reiner, Melchior Patrick, Furtw?ngler Rhoikos, Schlesner Matthias, Vokuhl Christian, R?cken Christoph, Johann Pascal D., Frühwald Michael C..
Clinical and molecular risk factors in extracranial malignant rhabdoid tumors: toward an integrated model of high-risk tumors.
https://doi.org/10.1158/1078-0432.ccr-23-3489
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Wiestler Benedikt, Bison Brigitte, Behrens Lars, Tüchert Stefanie, Metz Marie, Griessmair Michael, Jakob Marcus, Schlegel Paul-Gerhardt, Binder Vera, von Luettichau Irene, Metzler Markus, Johann Pascal, Hau Peter, Frühwald Michael.
Human-level differentiation of medulloblastoma from pilocytic astrocytoma: a real-world multicenter pilot study.
https://doi.org/10.3390/cancers16081474
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2023 |
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Kruchen Anne, Johann Pascal-David, Rekowski Laura, Müller Ingo.
Epigenetic modification of mesenchymal stromal cells derived from bone marrow and embryonal tumors to facilitate immunotherapeutic approaches in pediatric malignancies.
https://doi.org/10.3390/cimb45030136
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Kuhlen Michaela, Kunstreich Marina, Wudy Stefan A., Holterhus Paul-Martin, Lessel Lienhard, Schneider Dominik T., Brecht Ines B., Schewe Denis M., Seitz Guido, Roecken Christoph, Vokuhl Christian, Johann Pascal-David, Frühwald Michael C., Vorwerk Peter, Redlich Antje.
Outcome for pediatric adreno-cortical tumors is best predicted by the COG stage and five-item microscopic score — report from the German MET studies.
https://doi.org/10.3390/cancers15010225
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Johann Pascal-David, Altendorf Lea, Efremova Emma-Maria, Holsten Till, Steinbügl Mona, Nemes Karolina, Eckhardt Alicia, Kresbach Catena, Bockmayr Michael, Koch Arend, Haberler Christine, Antonelli Manila, DeSisto John, Schuhmann Martin U., Hauser Peter, Siebert Reiner, Bens Susanne, Kool Marcel, Green Adam L., Hasselblatt Martin, Frühwald Michael C., Schüller Ulrich.
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
https://doi.org/10.1007/s00401-023-02608-7
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Kuhlen Michaela, Kunstreich Marina, Lessel Lienhard, Wudy Stefan A., Holterhus Paul-Martin, Vokuhl Christian, Juettner Eva, Roecken Christoph, Seitz Guido, Slavetinsky Christoph, Fuchs J?rg, Schewe Denis M., Claus Rainer, Johann Pascal-David, Frühwald Michael C., Vorwerk Peter, Redlich Antje.
Refractory and relapsed paediatric ACC in the MET studies – a challenging situation necessitating novel diagnostic and therapeutic concepts.
https://doi.org/10.1016/j.ejcped.2023.100015
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Nemes Karolina, Benesch Martin, Kolarova Julia, Johann Pascal-David, Hasselblatt Martin, Thomas Christian, Bens Susanne, Glaser Selina, Ammerpohl Ole, Liaugaudiene Olga, Sadeghipour Alireza, von der Weid Nicolas, Schmid Irene, Gidding Corrie, Erdreich-Epstein Anat, Khurana Claudia, Ebetsberger-Dachs Georg, Lemmer Andreas, Khatib Ziad, Hernández Marqués Carmen, Pears Jane, Quehenberger Franz, Kordes Uwe, Vokuhl Christian, Gerss Joachim, Schwarz Heike, Bison Brigitte, Biegel Jaclyn A., Siebert Reiner, Frühwald Michael C..
Rhabdoid tumors in patients conceived following ART: is there an association?.
https://doi.org/10.1093/humrep/dead154
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2022 |
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Federico Aniello, Thomas Christian, Miskiewicz Katarzyna, Woltering Niklas, Zin Francesca, Nemes Karolina, Bison Brigitte, Johann Pascal-David, Hawes Debra, Bens Susanne, Kordes Uwe, Albrecht Steffen, Dohmen Hildegard, Hauser Peter, Keyvani Kathy, van Landeghem Frank K. H., Lund Eva L?bner, Scheie David, Mawrin Christian, Monoranu Camelia-Maria, Parm Ulh?i Benedicte, Pietsch Torsten, Reinhard Harald, Riemenschneider Markus J., Sehested Astrid, Sumerauer David, Siebert Reiner, Paulus Werner, Frühwald Michael C., Kool Marcel, Hasselblatt Martin.
ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.
https://doi.org/10.1007/s00401-022-02424-5
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Nemes Karolina, Johann Pascal-David, Tüchert Stefanie, Melchior Patrick, Vokuhl Christian, Siebert Reiner, Furtw?ngler Rhoikos, Frühwald Michael C..
Current and emerging therapeutic approaches for extracranial malignant rhabdoid tumors.
https://doi.org/10.2147/cmar.s289544
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Jurmeister Philipp, Gl?? Stefanie, Roller Renée, Leitheiser Maximilian, Schmid Simone, Mochmann Liliana H., Payá Capilla Emma, Fritz Rebecca, Dittmayer Carsten, Friedrich Corinna, Thieme Anne, Keyl Philipp, Jarosch Armin, Schallenberg Simon, Bl?ker Hendrik, Hoffmann Inga, Vollbrecht Claudia, Lehmann Annika, Hummel Michael, Heim Daniel, Haji Mohamed, Harter Patrick, Englert Benjamin, Frank Stephan, Hench Jürgen, Paulus Werner, Hasselblatt Martin, Hartmann Wolfgang, Dohmen Hildegard, Keber Ursula, Jank Paul, Denkert Carsten, Stadelmann Christine, Bremmer Felix, Richter Annika, Wefers Annika, Ribbat-Idel Julika, Perner Sven, Idel Christian, Chiariotti Lorenzo, Della Monica Rosa, Marinelli Alfredo, Schüller Ulrich, Bockmayr Michael, Liu Jacklyn, Lund Valerie J., Forster Martin, Lechner Matt, Lorenzo-Guerra Sara L., Hermsen Mario, Johann Pascal-David, Agaimy Abbas, Seegerer Philipp, Koch Arend, Heppner Frank, Pfister Stefan M., Jones David T. W., Sill Martin, von Deimling Andreas, Snuderl Matija, Müller Klaus-Robert, Forgó Erna, Howitt Brooke E., Mertins Philipp, Klauschen Frederick, Capper David.
DNA methylation-based classification of sinonasal tumors.
https://doi.org/10.1038/s41467-022-34815-3
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Nemes Karolina, Johann Pascal-David, Steinbügl Mona, Gruhle Miriam, Bens Susanne, Kachanov Denis, Teleshova Margarita, Hauser Peter, Simon Thorsten, Tippelt Stephan, Eberl Wolfgang, Chada Martin, Lopez Vicente Santa-Maria, Grigull Lorenz, Hernáiz-Driever Pablo, Eyrich Matthias, Pears Jane, Milde Till, Reinhard Harald, Leipold Alfred, van de Wetering Marianne, Gil-da-Costa Maria Jo?o, Ebetsberger-Dachs Georg, Kerl Kornelius, Lemmer Andreas, Boztug Heidrun, Furtw?ngler Rhoikos, Kordes Uwe, Vokuhl Christian, Hasselblatt Martin, Bison Brigitte, Kr?ncke Thomas, Melchior Patrick, Timmermann Beate, Gerss Joachim, Siebert Reiner, Frühwald Michael C..
Infants and newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB registry: a unique and challenging population.
https://doi.org/10.3390/cancers14092185
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Hasselblatt Martin, Thomas Christian, Federico Aniello, Bens Susanne, Hellstr?m Mats, Casar‐Borota Olivera, Kordes Uwe, Neumann Julia E., Dottermusch Matthias, Rodriguez Fausto J., Lo Andrea C., Cheng Sylvia, Hendson Glenda, Hukin Juliette, Hartmann Christian, Koch Arend, Capper David, Siebert Reiner, Paulus Werner, Nemes Karolina, Johann Pascal-David, Frühwald Michael C., Kool Marcel.
Low‐grade diffusely infiltrative tumour (LGDIT), SMARCB1‐mutant: a clinical and histopathological distinct entity showing epigenetic similarity with ATRT‐MYC.
https://doi.org/10.1111/nan.12797
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Blümel Lena, Qin Nan, Berlandi Johannes, Paisana Eunice, Casc?o Rita, Custódia Carlos, Pauck David, Picard Daniel, Langini Maike, Stühler Kai, Meyer Frauke-Dorothee, G?bbels Sarah, Malzkorn Bastian, Liebau Max C., Barata Jo?o T., Jeibmann Astrid, Kerl Kornelius, Erkek Serap, Kool Marcel, Pfister Stefan M., Johann Pascal-David, Frühwald Michael C., Borkhardt Arndt, Reifenberger Guido, Faria Claudia C., Fischer Ute, Hasselblatt Martin, Bartl Jasmin, Remke Marc.
Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.
https://doi.org/10.1038/s41419-022-05243-4
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Fincke Victoria E., Krulik Mateja E., Joshi Piyush, Frühwald Michael C., Chen Ying-Bei, Johann Pascal-David.
Renal medullary carcinomas harbor a distinct methylation phenotype and display aberrant methylation of genes related to early nephrogenesis.
https://doi.org/10.3390/cancers14205044
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Hasselblatt Martin, Thomas Christian, Federico Aniello, Nemes Karolina, Johann Pascal-David, Bison Brigitte, Bens Susanne, Dahlum Sonja, Kordes Uwe, Redlich Antje, Lessel Lienhard, Pajtler Kristian W., Mawrin Christian, Schüller Ulrich, Nolte Kay, Kramm Christof M., Hinz Felix, Sahm Felix, Giannini Caterina, Penkert Judith, Kratz Christian P., Pfister Stefan M., Siebert Reiner, Paulus Werner, Kool Marcel, Frühwald Michael C..
SMARCB1-deficient and SMARCA4-deficient malignant brain tumors with complex copy number alterations and TP53 mutations may represent the first clinical manifestation of Li-Fraumeni syndrome.
https://doi.org/10.1097/pas.0000000000001905
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Graf Monika, Interlandi Marta, Moreno Natalia, Holdhof D?rthe, G?bel Carolin, Melcher Viktoria, Mertins Julius, Albert Thomas K., Kastrati Dennis, Alfert Amelie, Holsten Till, de Faria Flavia, Meisterernst Michael, Rossig Claudia, Warmuth-Metz Monika, Nowak Johannes, Meyer zu H?rste Gerd, Mayère Chloe, Nef Serge, Johann Pascal-David, Frühwald Michael C., Dugas Martin, Schüller Ulrich, Kerl Kornelius.
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.
https://doi.org/10.1038/s41467-022-29152-4
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Johann Pascal-David.
“Adult rhabdoid tumors—a riddle inside an enigma?”.
https://doi.org/10.1038/s41379-022-01144-1
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2021 |
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Thomas Christian, Federico Aniello, Sill Martin, Bens Susanne, Oyen Florian, Nemes Karolina, Johann Pascal-David, Hartmann Christian, Hartmann Wolfgang, Sumerauer David, Paterno Vincenzo, Samii Amir, Kordes Uwe, Siebert Reiner, Frühwald Michael C., Paulus Werner, Kool Marcel, Hasselblatt Martin.
Atypical teratoid/rhabdoid tumor (AT/RT) with molecular features of pleomorphic xanthoastrocytoma.
https://doi.org/10.1097/pas.0000000000001694
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Steinbügl Mona, Nemes Karolina, Johann Pascal-David, Kr?ncke Thomas, Tüchert Stefanie, da Costa Maria Joao Gil, Ebinger Martin, Schüller Ulrich, Sehested Astrid, Hauser Peter, Reinhard Harald, Sumerauer David, Hettmer Simone, Jakob Marcus, Hasselblatt Martin, Siebert Reiner, Witt Olaf, Gerss Joachim, Kerl Kornelius, Frühwald Michael C..
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.
https://doi.org/10.1002/pbc.29267
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Johann Pascal-David, Wuchter Patrick, Trojanova Lenka, Sturm Dominik, Lu Kevin Hai-Ning, Kulozik Andreas E., Kunz Joachim B..
Cui Bono? Identifying patient groups that may benefit from granulocyte transfusions in pediatric hematology and oncology.
https://doi.org/10.1097/mph.0000000000002349
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Zin Francesca, Cotter Jennifer A., Haberler Christine, Dottermusch Matthias, Neumann Julia, Schüller Ulrich, Schweizer Leonille, Thomas Christian, Nemes Karolina, Johann Pascal-David, Kool Marcel, Frühwald Michael C., Paulus Werner, Judkins Alexander, Hasselblatt Martin.
Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup.
https://doi.org/10.1111/bpa.12967
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Pathak Rajiv, Zin Francesca, Thomas Christian, Bens Susanne, Gayden Tenzin, Karamchandani Jason, Dudley Roy W., Nemes Karolina, Johann Pascal-David, Oyen Florian, Kordes Uwe, Jabado Nada, Siebert Reiner, Paulus Werner, Kool Marcel, Frühwald Michael C., Albrecht Steffen, Kalpana Ganjam V., Hasselblatt Martin.
Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.
https://doi.org/10.1007/s00401-021-02328-w
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Marcu Ana, Schlosser Andreas, Keupp Anne, Trautwein Nico, Johann Pascal-David, W?lfl Matthias, Lager Johanna, Monoranu Camelia Maria, Walz Juliane S, Henkel Lisa M, Krau? Jürgen, Ebinger Martin, Schuhmann Martin, Thomale Ulrich Wilhelm, Pietsch Torsten, Klinker Erdwine, Schlegel Paul G, Oyen Florian, Reisner Yair, Rammensee Hans-Georg, Eyrich Matthias.
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors.
https://doi.org/10.1136/jitc-2021-003404
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Johann Pascal-David, Lenz Dominic, Ries Markus.
The drug development pipeline for glioblastoma: a cross sectional assessment of the FDA orphan drug product designation database.
https://doi.org/10.1371/journal.pone.0252924
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van Tilburg Cornelis M., Pfaff Elke, Pajtler Kristian W., Langenberg Karin P. S., Fiesel Petra, Jones Barbara C., Balasubramanian Gnana Prakash, Stark Sebastian, Johann Pascal-David, Blattner-Johnson Mirjam, Schramm Kathrin, Dikow Nicola, Hirsch Steffen, Sutter Christian, Grund Kerstin, von Stackelberg Arend, Kulozik Andreas E., Lissat Andrej, Borkhardt Arndt, Meisel Roland, Reinhardt Dirk, Klusmann Jan-Henning, Fleischhack Gudrun, Tippelt Stephan, von Schweinitz Dietrich, Schmid Irene, Kramm Christof M., von Bueren Andre O., Calaminus Gabriele, Vorwerk Peter, Graf Norbert, Westermann Frank, Fischer Matthias, Eggert Angelika, Burkhardt Birgit, Wossmann Wilhelm, Nathrath Michaela, Hecker-Nolting Stefanie, Frühwald Michael C., Schneider Dominik T., Brecht Ines B, Ketteler Petra, Fulda Simone, Koscielniak Ewa, Meister Michael T., Scheer Monika, Hettmer Simone, Schwab Matthias, Tremmel Roman, Ora Ingrid, Hutter Caroline, Gerber Nicolas U., Lohi Olli, Kazanowska Bernarda, Kattamis Antonis, Filippidou Maria, Goemans Bianca, Zwaan C. Michel, Milde Till, Jager Natalie, Wolf Stephan, Reuss David, Sahm Felix, von Deimling Andreas, Dirksen Uta, Freitag Angelika, Witt Ruth, Lichter Peter, Kopp-Schneider Annette, Jones David T. W., Molenaar Jan J., Capper David, Pfister Stefan M., Witt Olaf.
The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
https://doi.org/10.1158/2159-8290.cd-21-0094
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2020 |
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Bremer Juliane, Kottke Raimund, Johann Pascal-David, Hoff Katja, Brazzola Pierluigi, Grotzer Michael A., Kool Marcel, Rushing Elisabeth, Gerber Nicolas U..
A single supratentorial high‐grade neuroepithelial tumor with two distinct BCOR mutations, exceptionally long complete remission and survival.
https://doi.org/10.1002/pbc.28384
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Holdhof D?rthe, Johann Pascal-David, Spohn Michael, Bockmayr Michael, Safaei Sepehr, Joshi Piyush, Masliah-Planchon Julien, Ho Ben, Andrianteranagna Mamy, Bourdeaut Franck, Huang Annie, Kool Marcel, Upadhyaya Santhosh A., Bendel Anne E., Indenbirken Daniela, Foulkes William D., Bush Jonathan W., Creytens David, Kordes Uwe, Frühwald Michael C., Hasselblatt Martin, Schüller Ulrich.
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.
https://doi.org/10.1007/s00401-020-02250-7
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Thomas Christian, Wefers Annika, Bens Susanne, Nemes Karolina, Agaimy Abbas, Oyen Florian, Vogelgesang Silke, Rodriguez Fausto J., Brett Francesca M., McLendon Roger, Bodi Istvan, Burel-Vandenbos Fanny, Keyvani Kathy, Tippelt Stefan, Poulsen Frantz R., Lipp Eric S., Giannini Caterina, Reifenberger Guido, Kuchelmeister Klaus, Pietsch Torsten, Kordes Uwe, Siebert Reiner, Frühwald Michael C., Johann Pascal-David, Sill Martin, Kool Marcel, Deimling Andreas von, Paulus Werner, Hasselblatt Martin.
Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults.
https://doi.org/10.1007/s00401-019-02094-w
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Johann Pascal-David.
Invited review: dysregulation of chromatin remodellers in paediatric brain tumours – SMARCB1 and beyond.
https://doi.org/10.1111/nan.12616
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Theruvath Johanna, Sotillo Elena, Mount Christopher W., Graef Claus Moritz, Delaidelli Alberto, Heitzeneder Sabine, Labanieh Louai, Dhingra Shaurya, Leruste Amaury, Majzner Robbie G., Xu Peng, Mueller Sabine, Yecies Derek W., Finetti Martina A., Williamson Daniel, Johann Pascal-David, Kool Marcel, Pfister Stefan, Hasselblatt Martin, Frühwald Michael C., Delattre Olivier, Surdez Didier, Bourdeaut Franck, Puget Stephanie, Zaidi Sakina, Mitra Siddhartha S., Cheshier Samuel, Sorensen Poul H., Monje Michelle, Mackall Crystal L..
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
https://doi.org/10.1038/s41591-020-0821-8
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Kuwahara Yasumichi, Iehara Tomoko, Ichise Eisuke, Katsumi Yoshiki, Ouchi Kazutaka, Tsuchiya Kunihiko, Miyachi Mitsuru, Konichi Eiichi, Sasajima Hiroyasu, Nakamura Satoaki, Fumino Shigehisa, Tajiri Tatsuro, Johann Pascal-David, Frühwald Michael C., Yoshida Tatsushi, Okuda Tsukasa, Hosoi Hajime.
Novel two MRT cell lines established from multiple sites of a synchronous MRT patient.
https://doi.org/10.21873/anticanres.14636
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Hasselblatt M., Thomas C., Nemes K., Monoranu C.‐M., Riemenschneider M. J., Koch A., Sumerauer D., Hauser P., Paulus W., Johann Pascal-David, Kool M., Frühwald Michael C..
Tyrosinase immunohistochemistry can be employed for the diagnosis of atypical teratoid/rhabdoid tumours of the tyrosinase subgroup (ATRT‐TYR).
https://doi.org/10.1111/nan.12560
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2019 |
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Frühwald Michael C., Hasselblatt Martin, Nemes Karolina, Bens Susanne, Steinbügl Mona, Johann Pascal-David, Kerl Kornelius, Hauser Peter, Quiroga Eduardo, Solano-Paez Palma, Biassoni Veronica, Gil-da-Costa Maria Joao, Perek-Polnik Martha, van de Wetering Marianne, Sumerauer David, Pears Jane, Stabell Niklas, Holm Stefan, Hengartner Heinz, Gerber Nicolas U., Grotzer Michael, Boos Joachim, Ebinger Martin, Tippelt Stefan, Paulus Werner, Furtw?ngler Rhoikos, Hernáiz-Driever Pablo, Reinhard Harald, Rutkowski Stefan, Schlegel Paul-Gerhardt, Schmid Irene, Kortmann Rolf-Dieter, Timmermann Beate, Warmuth-Metz Monika, Kordes Uwe, Gerss Joachim, Nysom Karsten, Schneppenheim Reinhard, Siebert Reiner, Kool Marcel, Graf Norbert.
Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors.
https://doi.org/10.1093/neuonc/noz244
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Erkek Serap, Johann Pascal-David, Finetti Martina A., Drosos Yiannis, Chou Hsien-Chao, Zapatka Marc, Sturm Dominik, Jones David T. W., Korshunov Andrey, Rhyzova Marina, Wolf Stephan, Mallm Jan-Philipp, Beck Katja, Witt Olaf, Kulozik Andreas E., Frühwald Michael C., Northcott Paul A., Korbel Jan O., Lichter Peter, Eils Roland, Gajjar Amar, Roberts Charles W. M., Williamson Daniel, Hasselblatt Martin, Chavez Lukas, Pfister Stefan M., Kool Marcel.
Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation.
https://doi.org/10.1016/j.ccell.2018.11.014
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Tegeder Isabel, Thiel Katharina, Erkek Serap, Johann Pascal-David, Berlandi Johannes, Thatikonda Venu, Frühwald Michael C., Kool Marcel, Jeibmann Astrid, Hasselblatt Martin.
Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors.
https://doi.org/10.1007/s11060-018-03018-6
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Bleeke Matthias, Johann Pascal-David, Gr?bner Susanne, Alten Julia, Cario Gunnar, Sch?fer Hansj?rg, Klapper Wolfram, Khoury Joseph, Pfister Stefan, Müller Ingo.
Genome‐wide analysis of acute leukemia and clonally related histiocytic sarcoma in a series of three pediatric patients.
https://doi.org/10.1002/pbc.28074
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Chun Hye-Jung E., Johann Pascal-David, Milne Katy, Zapatka Marc, Buellesbach Annette, Ishaque Naveed, Iskar Murat, Erkek Serap, Wei Lisa, Tessier-Cloutier Basile, Lever Jake, Titmuss Emma, Topham James T., Bowlby Reanne, Chuah Eric, Mungall Karen L., Ma Yussanne, Mungall Andrew J., Moore Richard A., Taylor Michael D., Gerhard Daniela S., Jones Steven J. M., Korshunov Andrey, Gessler Manfred, Kerl Kornelius, Hasselblatt Martin, Frühwald Michael C., Perlman Elizabeth J., Nelson Brad H., Pfister Stefan M., Marra Marco A., Kool Marcel.
Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration.
https://doi.org/10.1016/j.celrep.2019.10.013
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Ho Ben, Johann Pascal-David, Grabovska Yura, De Dieu Andrianteranagna Mamy Jean, Yao Fupan, Frühwald Michael C., Hasselblatt Martin, Bourdeaut Franck, Williamson Daniel, Huang Annie, Kool Marcel.
Molecular subgrouping of atypical teratoid/rhabdoid tumors: a reinvestigation and current consensus.
https://doi.org/10.1093/neuonc/noz235
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Johann Pascal-David, J?ger Natalie, Pfister Stefan M., Sill Martin.
RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression.
https://doi.org/10.1186/s12859-019-3014-z
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Thomas Christian, Knerlich-Lukoschus Friederike, Reinhard Harald, Johann Pascal-David, Sturm Dominik, Sahm Felix, Bens Susanne, Vogt Julia, Nemes Karolina, Oyen Florian, Kordes Uwe, Siebert Reiner, Schneppenheim Reinhard, Messing-Jünger Martina, Pietsch Torsten, von Deimling Andreas, Paulus Werner, Pfister Stefan M., Kool Marcel, Frühwald Michael C., Hasselblatt Martin.
Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1.
https://doi.org/10.1007/s00401-019-02001-3
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2018 |
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Galarza Natalia Moreno, Holdhof D?rthe, Interlandi Marta, Melcher Viktoria, Graf Monika, Kastrati Dennis, Meisterernst Michael, Johann Pascal-David, Kool Marcel, Frühwald Michael C., Schüller Ulrich, Kerl Kornelius.
ATRT-07. Murine Sox2-positive early precursor cells give rise to rhabdoid tumors with features of the human ATRT-MYC group.
https://doi.org/10.1093/neuonc/noy059.006
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Marcu Ana, Trautwein Nico, Stevanovic Stefan, Johann Pascal-David, Technau Antje, Lager Johanna, Monoranu Camelia-Maria, Henkel Lisa, Krau? Jürgen, Ebinger Martin, Schuhmann Martin, Thomale Ulrich, Pietsch Torsten, W?lfl Matthias, Schlegel Paul Gerhardt, Frühwald Michael C., Oyen Florian, Reisner Yair, Rammensee Hans-Georg, Eyrich Matthias.
IMMU-28. Deciphering the AT/RT ligandome.
https://doi.org/10.1093/neuonc/noy059.344
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